5. Great White Plaque
Tuberculosis has been “ruining” the human population throughout history. Starting from the 1600s, the European TB epidemic known as the Great White Plague was taking lives for more than 200 years. Every 7th infected person died. Tuberculosis has been a constant problem of colonial America. Even in the late 19th century, this disease was the reason for 10 percent of all deaths in the US.
6. Yellow fever
Together with African slaves, Europeans brought to America a number of new diseases, and yellow fever was among the most horrible ones. It has destroyed the entire cities. When the French Emperor Napoleon sent an army of 33,000 French soldiers to North America, yellow fever killed 29,000 of them.